Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
AUTOREGULATION OF PORTAL CIRCULATION - A CORRELATIVE STUDY OF CIRCULATION AND VASCULAR MORPHOLOGY
Autore:
NANJO H; MASUDA H; SATO T; KAWAMURA K; ASANUMA Y; KOYAMA K;
Indirizzi:
AKITA UNIV,SCH MED,DEPT PATHOL 2 AKITA 010 JAPAN AKITA UNIV,SCH MED,DEPT SURG 1 AKITA 010 JAPAN
Titolo Testata:
Pathology international
fascicolo: 9, volume: 47, anno: 1997,
pagine: 585 - 591
SICI:
1320-5463(1997)47:9<585:AOPC-A>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLOOD-FLOW; VENOUS RESISTANCE; RAT MODEL; HYPERTENSION; STIMULATION; MECHANISMS; PRESSURE; SYSTEM; DOG;
Keywords:
AUTOREGULATION; HEPATIC CIRCULATION; PORTAL CIRCULATION; PORTAL VENOUS FLOW; PORTAL VENOUS RESISTANCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
H. Nanjo et al., "AUTOREGULATION OF PORTAL CIRCULATION - A CORRELATIVE STUDY OF CIRCULATION AND VASCULAR MORPHOLOGY", Pathology international, 47(9), 1997, pp. 585-591

Abstract

To investigate the mechanism of portal circulation and the genesis ofportal hypertension, an in vivo model was made to increase portal venous flow (PVF) by forming a bypass shunt between the femoral artery tothe splenic venous branch in pigs and dogs via a regulatable pump. Using this model, an autoregulatory hemodynamics of the portal circulation and corresponding morphological changes of the intrahepatic vascular system were determined, Immediately after blood flow increase (100 mL/min) to the portal vein, PVF increased to the baseline level plus bypass shunt flow, But, PVF returned to the baseline level within 1 h for both animals, Portal venous resistance (PVR) at 1 h was significantly higher than the baseline level (P<0.05). By histometric analysis of the cross-sectional area of the portal and hepatic venous branches (CSA-PV, CSA-HV) using the biopsized liver, CSA-HV at 1 h was 27.6% of the CSA-HV of the baseline level in dog, which showed narrowing and contractive changes of the hepatic venous branches, and CSA-PV at 1 h was 36.4% of the CSA-PV of the baseline level in pig, which showed narrowing and contractive changes of the portal venous branches, It is suggested that a tone of the intrahepatic vascular system has an important role in the portal autoregulatory hemodynamics.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 12:57:44