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Titolo:
SEXUAL IMPOTENCE IS ASSOCIATED WITH A REDUCED PRODUCTION OF OXYTOCIN AND WITH AN INCREASED PRODUCTION OF OPIOID-PEPTIDES IN THE PARAVENTRICULAR NUCLEUS OF MALE-RATS
Autore:
ARLETTI R; CALZA L; GIARDINO L; BENELLI A; CAVAZZUTI E; BERTOLINI A;
Indirizzi:
UNIV MODENA,DEPT BIOMED SCI,PHARMACOL SECT,VIA G CAMPI 287 I-41100 MODENA ITALY HESPERIA HOSP,PATHOPHYSIOL CTR NERVOUS SYST I-41100 MODENA ITALY
Titolo Testata:
Neuroscience letters
fascicolo: 2-3, volume: 233, anno: 1997,
pagine: 65 - 68
SICI:
0304-3940(1997)233:2-3<65:SIIAWA>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
COPULATORY-BEHAVIOR; MESSENGER-RNA; GALANIN; EXPRESSION; SEQUENCE;
Keywords:
SEXUAL IMPOTENCE; PARAVENTRICULAR NUCLEUS; OXYTOCIN MESSENGER-RNA; PROENKEPHALIN MESSENGER-RNA; PRO-DYNORPHIN MESSENGER-RNA; IN SITU HYBRIDIZATION; RAT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
R. Arletti et al., "SEXUAL IMPOTENCE IS ASSOCIATED WITH A REDUCED PRODUCTION OF OXYTOCIN AND WITH AN INCREASED PRODUCTION OF OPIOID-PEPTIDES IN THE PARAVENTRICULAR NUCLEUS OF MALE-RATS", Neuroscience letters, 233(2-3), 1997, pp. 65-68

Abstract

Oxytocin plays a physiological stimulatory role on sexual behavior. Conversely, opioid neuropeptides play a physiological inhibitory role. Here we show that in sexually impotent rats there is a reduced expression of oxytocin mRNA and an increased expression of proenkephalin and pro-dynorphin mRNA in the paraventricular nucleus of hypothalamus (PVN), a brain structure of key importance for sexual behavior. These datasuggest that an imbalance in the production of oxytocin and of opioidpeptides in the PVN, with prevalence of opioid peptides, may underliea condition of sexual impotence. (C) 1997 Elsevier Science Ireland Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 05:37:47