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Titolo:
ASSESSMENT OF HEMODYNAMIC-CHANGES IN PATIENTS WITH RENAL-ARTERY STENOSIS BY MEANS OF THE CINE MR PHASE-CONTRAST TECHNIQUE
Autore:
SCHOENBERG SO; KNOPP MV; BOCK M; KALLINOWSKI F; JUST A; ESSIG M; HAWIGHORST H; ZUNA I; SCHAD L; ALLENBERG JR; VANKAICK G;
Indirizzi:
DEUTSCH KREBSFORSCHUNGSZENTRUM,ABT RADIOL DIAGNOST & THERAPIE D-69120HEIDELBERG GERMANY UNIV HEIDELBERG,CHIRURG KLIN,SEKT GEFASSCHIRURG HEIDELBERG GERMANY UNIV HEIDELBERG,INST PHYSIOL 1 D-6900 HEIDELBERG GERMANY
Titolo Testata:
Radiologe
fascicolo: 8, volume: 37, anno: 1997,
pagine: 651 - 662
SICI:
0033-832X(1997)37:8<651:AOHIPW>2.0.ZU;2-G
Fonte:
ISI
Lingua:
GER
Soggetto:
DIGITAL SUBTRACTION ANGIOGRAPHY; BLOOD-FLOW; RENOVASCULAR HYPERTENSION; DOWNSTREAM CIRCULATION; EXERCISE RENOGRAPHY; CONSCIOUS DOGS; SLOWED SYSTOLE; GADOLINIUM; TARDUS; PREVALENCE;
Keywords:
MAGNETIC RESONANCE; FLOW DYNAMICS; RENAL ARTERY STENOSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
42
Recensione:
Indirizzi per estratti:
Citazione:
S.O. Schoenberg et al., "ASSESSMENT OF HEMODYNAMIC-CHANGES IN PATIENTS WITH RENAL-ARTERY STENOSIS BY MEANS OF THE CINE MR PHASE-CONTRAST TECHNIQUE", Radiologe, 37(8), 1997, pp. 651-662

Abstract

Purpose: To evaluate the use of high-temporal resolution cine MR phase-contrast flow measurements for assessment of flow dynamics in renal artery stenosis (RAS). Material and methods: In a dog model, cine MR flow measurements were validated by comparing the MR flow data to an invasive transit-time ultrasound reference technique for different degrees of RAS. Cardiac-gated MR flow curves were recorded in 56 renal arteries of 28 patients with a temporal resolutions of at least 32 ms. In all cases RAS was confirmed by digital subtraction angiography (DSA). Abnormalities of flow dynamics were assessed in the calculated flow curves using the MR parameters mean flow, maximum velocity, and time to systolic maximum. Results: By means of the MR blood flow parameters high-grade stenoses (>50%, n=23) were detected with sensitivity of 100% and specificity of 94% with reference to DSA. The overall differentiation between stenoses (n=37) and non-stenosed vessels (n=19) revealed asensitivity of 87% and a specificity of 100%. Conclusion: Analysis ofcardiac-gated MR flow curves provides a non-invasive method to assessthe hemodynamic significance of RAS and thus allows a functional evaluation in relation to the morphologic characteristics of the stenosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 12:47:30