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Title
Thin-layer chromatography and mass spectrometry for screening of biological samples for drugs and metabolites
Author:
Brzezinka, H; Dallakian, P; Budzikiewicz, H;
Addresses:
Univ Bonn, Inst Rechtsmed, D-53111 Bonn, Germany Univ Bonn Bonn Germany D-53111 nn, Inst Rechtsmed, D-53111 Bonn, Germany Univ Cologne, Inst Organ Chem, D-50939 Cologne, Germany Univ Cologne Cologne Germany D-50939 rgan Chem, D-50939 Cologne, Germany
Heading Title:
JPC-JOURNAL OF PLANAR CHROMATOGRAPHY-MODERN TLC
issue: 2, volume: 12, year: 1999,
pages: 96 - 108
SICI:
0933-4173(199903/04)12:2<96:TCAMSF>2.0.ZU;2-L
Source:
ISI
Language:
ENG
Subject:
SYSTEMATIC TOXICOLOGICAL ANALYSIS; GAS-CHROMATOGRAPHY; IDENTIFICATION; TLC; FTIR; LSD;
Keywords:
off-line TLC-MS; El mass spectrometry; drugs; metabolites;
Document Type:
Article
Nature:
Serial
Edition:
Physical, Chemical & Earth Sciences
Citations:
19
Reviewed:
Addresses for extracts:
Address: Brzezinka, H Univ Bonn, Inst Rechtsmed, Stiftspl 12, D-53111 Bonn, GermanyUniv Bonn Stiftspl 12 Bonn Germany D-53111 111 Bonn, Germany
Citation:
H. Brzezinka and others, "Thin-layer chromatography and mass spectrometry for screening of biological samples for drugs and metabolites", J PL CHROM, 12(2), 1999, pp. 96-108

Abstract

This paper describes a method for off-line coupling of thin-layer chromatography (TLC) and electron-impact ionization mass spectrometry (EIMS) which is well suited for routine forensic and toxicological investigations of a large number of samples. The advantages and drawbacks of this approach are discussed. Several TLC systems for 493 compounds of forensic and toxicological interest are described and eight-peak mass spectra from full EI mass spectra are listed.

ASDD Area Sistemi Dipartimentali e Documentali, Bologna University, Review Catalogue
Document created on 21/10/19 at 04:44:57