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Detection of a drug-resistant human immunodeficiency virus variant in a newly infected heterosexual couple
CLINICAL INFECTIOUS DISEASES
The dynamic of adherence to highly active antiretroviral therapy: Results from the French National APROCO cohort
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
Low frequency of severe hepatotoxicity and association with HCV coinfection in HIV-positive patients treated with HAART
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
Genotypic correlates of a virologic response to stavudine after zidovudinemonotherapy
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
Stavudine versus zidovudine and the development of lipodystrophy
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
Patterns of resistance mutations to antiretroviral drugs in extensively treated HIV-1-Infected patients with failure of highly active antiretroviral therapy
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
Zidovudine and stavudine sequencing in HIV treatment planning: Findings from the CHORUS HIV cohort
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
Resistance analyses in HIV infected patients with a history of multiple antiretroviral treatment regimens
SEXUALLY TRANSMITTED INFECTIONS
Mutational patterns in the HIV genome and cross-resistance following nucleoside and nucleotide analogue drug exposure
ANTIVIRAL THERAPY
Current insights into reverse transcriptase inhibitor-associated resistance
ANTIVIRAL THERAPY
Thymidine-analog and multi-nucleoside resistance mutations are observed inboth zidovudine-naive and zidovudine-experienced subjects with viremia after treatment with stavudine-containing regimens
JOURNAL OF HUMAN VIROLOGY
Gynecomastia associated with highly active antiretroviral therapy
ANNALS OF PHARMACOTHERAPY
Value of patient self-report and plasma human immunodeficiency virus protease inhibitor level as markers of adherence to antiretroviral therapy: Relationship to virologic response
CLINICAL INFECTIOUS DISEASES
Symptomatic lactic acidosis in hospitalized antiretroviral-treated patients with human immunodeficiency virus infection: A report of 12 cases
CLINICAL INFECTIOUS DISEASES
Synthesis and evaluation of novel amidate prodrugs of PMEA and PMPA
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Severe lactic acidosis and thiamine administration in an HIV-infected patient on HAART
INTERNATIONAL JOURNAL OF STD & AIDS
Making the most of sparse clinical data by using a predictive-model-based analysis, illustrated with a stavudine pharmacokinetic study
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
Combination therapy with saquinavir soft gelatin capsules in children withhuman immunodeficiency virus infection
PEDIATRIC INFECTIOUS DISEASE JOURNAL
Impact of HIV type 1 drug resistance mutations and phenotypic resistance profile on virologic response to salvage therapy
AIDS RESEARCH AND HUMAN RETROVIRUSES
Determination of pharmacokinetic parameters of stavudine in Japanese patients infected with HIV-1, using a Gaussian-like input rate function
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
Sequencing antiretroviral drugs
AIDS
Incidence of pancreatitis in HIV-infected patients receiving nucleoside reverse transcriptase inhibitor drugs
AIDS
Overview of the effectiveness of triple combination therapy in antiretroviral-naive HIV-1 infected adults
AIDS
Effects of treatment intensification with hydroxyurea in HIV-infected patients with virologic suppression
AIDS
Failure of stavudine-lamivudine combination therapy in antiretroviral-naive patients with AZT-like HIV-1 resistance mutations
JOURNAL OF MEDICAL VIROLOGY
Do patents for antiretroviral drugs constrain access to AIDS treatment in Africa?
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
In vivo pharmacokinetics and metabolism of anti-human immunodeficiency virus agent D4T-5 '-[P-bromophenyl methoxyalaninyl phosphate] (sampidine) in mice
DRUG METABOLISM AND DISPOSITION
A randomized, double-blind study of triple nucleoside therapy of abacavir,lamivudine, and zidovudine versus lamivudine and zidovudine in previously treated human immunodeficiency virus type 1-infected children
PEDIATRICS
Increased ability for selection of zidovudine resistance in a distinct class of wild-type HIV-1 from drug-naive persons
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Didanosine dosed once daily is equivalent to twice daily dosing for patients on double or triple combination antiretroviral therapy
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
Interaction of methadone with didanosine and stavudine
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
Determination of stavudine in human plasma and urine by high-performance liquid chromatography using a reduced sample volume
JOURNAL OF CHROMATOGRAPHY B
Incidence and impact of resistance against approved antiretroviral drugs
REVIEWS IN MEDICAL VIROLOGY
Phosphoramidate derivatives of stavudine as inhibitors of HIV: unnatural amino acids may substitute for alanine
ANTIVIRAL CHEMISTRY & CHEMOTHERAPY
Pharmaceutical relationships of three solid state forms of stavudine
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Conditions of selection of 'thymidine analogue mutations' (TAMs) in naive patients receiving different antiretroviral combinations including d4T.
PATHOLOGIE BIOLOGIE
Hepatic steatosis and lactic acidosis caused by stavudine in an HIV-infected patient
NETHERLANDS JOURNAL OF MEDICINE
A randomised, open-label comparison of three highly active antiretroviral therapy regimens including two nucleoside analogues and indinavir for previously untreated HIV-1 infection: the OzCombo1 study
AIDS
The effect of treatment intensification in HIV-infection: a study comparing treatment with ritonavir/saquinavir and ritonavir/saquinavir/stavudine
AIDS
Phenotypic and genotypic resistance patterns of HIV-1 isolates derived from individuals treated with didanosine and stavudine
AIDS
A randomized, comparative study of lamivudine plus stavudine, with indinavir or nelfinavir, in treatment-experienced HIV-infected patients
AIDS
Didanosine once daily: potential for expanded use
AIDS
Zidovudine triphosphate and lamivudine triphosphate concentration-responserelationships in HIV-infected persons
AIDS
Long-term hydroxyurea in combination with didanosine and stavudine for thetreatment of HIV-1 infection
AIDS
Concentrations of nevirapine, lamivudine and stavudine in semen of HIV-1-infected men
AIDS
Cerebrospinal fluid HIV-1 RNA during treatment with ritonavir/saquinavir or ritonavir/saquinavir/stavudine
AIDS
A comparison of stavudine plus lamivudine versus zidovudine plus lamivudine in combination with indinavir in antiretroviral naive individuals with HIV infection: selection of thymidine analog regimen therapy (START I)
AIDS
A comparison of stavudine, didanosine and indinavir with zidovudine, lamivudine and indinavir for the initial treatment of HIV-1 infected individuals: Selection of thymidine analog regimen therapy (START II)
AIDS
A randomized, dose-finding study with didanosine plus stavudine versus didanosine alone in antiviral-naive, HIV-infected Thai patients
AIDS
Lactic acidosis in the setting of antiretroviral therapy for the acquired immunodeficiency syndrome - A case report and review of the literature
AMERICAN JOURNAL OF NEPHROLOGY
Causes of macrocytosis in HIV-infected patients not treated with zidovudine
JOURNAL OF INFECTION
Differential removal of thymidine nucleotide analogues from blocked DNA chains by human immunodeficiency virus reverse transcriptase in the presence of physiological concentrations of 2 '-deoxynucleoside triphosphates
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Transplacental pharmacokinetics and fetal distribution of 2 ',3 '-didehydro-3 '-deoxythymidine (d4T) and its metabolites in late-term rhesus macaques
TERATOLOGY
Fatal lactic acidosis in a patient with acquired immunodeficiency syndrometreated with highly active antiretroviral therapy. Report one case
REVISTA MEDICA DE CHILE
Antiretroviral therapy of HIV infection in children
PEDIATRIC CLINICS OF NORTH AMERICA
The mechanism of phosphorylation of anti-HIV D4T by nucleoside diphosphatekinase
MOLECULAR PHARMACOLOGY
Clinical and virologic response to combination treatment with indinavir, zidovudine, and lamivudine in children with human immunodeficiency virus-1 infection: A multicenter study in The Netherlands
JOURNAL OF PEDIATRICS
Safety and efficacy of interferon-ribavirin combination therapy in HCV-HIVcoinfected subjects: an early report
GUT
Current situation of nucleosidic reverse transcriptase inhibitors
ANNALES DE MEDECINE INTERNE
Acute pancreatitis associated with severe lactic acidosis in human immunodeficiency virus-infected patients receiving triple therapy
JAC. Journal of antimicrobial chemotherapy
Efavirenz, nelfinavir, and stavudine rescue combination therapy in HIV-1-positive patients heavily pretreated with nucleoside analogues and protease inhibitors
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
Safety and antiretroviral effects of combined didanosine and stavudine therapy in HIV-infected individuals with CD4 counts of 200 to 500 cells/mm(3)
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY
Antiinfectives update: Focus on treatment and prevention of viral and associated infections
ANNALS OF PHARMACOTHERAPY
Antiretroviral therapy and prophylaxis of maternal fetal transmission of HIV-1. Current and future strategies.
ARCHIVES DE PEDIATRIE
Highly active antiretroviral therapy (HAART) for the treatment of infection with human immunodeficiency virus type 1
BIOMEDICINE & PHARMACOTHERAPY
Stavudine and the peripheral nerve in HIV-1 infected patients
JOURNAL OF NEUROLOGY
Lamivudine in combination with zidovudine stavudine, or didanosine in patients with HIV-1 infection. A randomized, double-blind, placebo-controlled trial
AIDS
Stavudine in zidovudine (ZDV)-experienced compared with ZDV-naive patients
AIDS
A syndrome of peripheral fat wasting (lipodystrophy) in patients receivinglong-term nucleoside analogue therapy
AIDS
Emergence of zidovudine and multidrug-resistance mutations in the HIV-1 reverse transcriptase gene in therapy-naive patients receiving stavudine plusdidanosine combination therapy
AIDS
Virological and immunological responses to once-daily dosing of didanosinein combination with stavudine
AIDS
Insertion of two amino acids combined with changes in reverse transcriptase containing tyrosine-215 of HIV-1 resistant to multiple nucleoside analogs
AIDS
The safety profile and antiviral activity of the combination of stavudine,didanosine, and nelfinavir in patients with HIV infection
CLINICAL THERAPEUTICS
Mutations conferring resistance to zidovudine diminish the antiviral effect of stavudine plus didanosine
JOURNAL OF MEDICAL VIROLOGY
Combination therapy with stavudine (d47) plus didanosine (ddI) in childrenwith human immunodeficiency virus infection
PEDIATRICS
Stavudine - An update of its use in the treatment of HIV infection
DRUGS
In vitro models to predict the in vivo mechanism, rate, and extent of placental transfer of dideoxynucleoside drugs against human immunodeficiency virus
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
INDEPENDENT SYNTHESIS AND FATE STUDIES OF IMPURITIES IN-PROCESS INTERMEDIATES OF THE ANTI-AIDS DRUG D4T
Organic process research & development
A SINGLE-DOSE STUDY TO ASSESS THE PENETRATION OF STAVUDINE INTO HUMANCEREBROSPINAL-FLUID IN ADULTS
Journal of acquired immune deficiency syndromes and human retrovirology
Mutations in the human immunodeficiency virus type 1 reverse transcriptasegene observed in stavudine and didanosine strains obtained by in vitro passages
RESEARCH IN VIROLOGY
COMPARISON OF 2 ANTIRETROVIRAL TRIPLE COMBINATIONS INCLUDING THE PROTEASE INHIBITOR INDINAVIR IN CHILDREN INFECTED WITH HUMAN-IMMUNODEFICIENCY-VIRUS
The Pediatric infectious disease journal
A PLACEBO-CONTROLLED TRIAL OF DIDANOSINE PLUS STAVUDINE, WITH AND WITHOUT HYDROXYUREA, FOR HIV-INFECTION
AIDS
ANTIVIRAL EFFECT OF DOUBLE AND TRIPLE-DRUG COMBINATIONS AMONGST HIV-INFECTED ADULTS - LESSONS FROM THE IMPLEMENTATION OF VIRAL LOAD-DRIVEN ANTIRETROVIRAL THERAPY
AIDS
EFFICACY AND SAFETY OF STAVUDINE AND DIDANOSINE COMBINATION THERAPY IN ANTIRETROVIRAL-EXPERIENCED PATIENTS
AIDS
COTRIMOXAZOLE AND STAVUDINE INTERFERENCE IN A HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ANALYSIS FOR DIDANOSINE IN HUMAN PLASMA
Therapeutic drug monitoring
A NEW THYMINE FREE SYNTHESIS OF THE ANTI-AIDS DRUG D4T VIA REGIO STEREO CONTROLLED BETA-ELIMINATION OF BROMOACETATES/
Tetrahedron letters
A PHASE I II STUDY OF THE PROTEASE INHIBITOR RITONAVIR IN CHILDREN WITH HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION/
Pediatrics
A RANDOMIZED COMPARATIVE TRIAL OF STAVUDINE (D4T) VERSUS ZIDOVUDINE (ZDV, AZT) IN CHILDREN WITH HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION
Pediatrics
THE TRANSPORT OF THE ANTI-HIV DRUG, 2',3'-DIDEHYDRO-3'DEOXYTHYMIDINE (D4T), ACROSS THE BLOOD-BRAIN AND BLOOD CEREBROSPINAL-FLUID BARRIERS
British Journal of Pharmacology
EFFICACY AND TOLERABILITY OF STAVUDINE PLUS LAMIVUDINE IN TREATMENT-NAIVE AND TREATMENT-EXPERIENCED PATIENTS WITH HIV-1 INFECTION
Annals of internal medicine
PHARMACOTHERAPY OF HIV DEMENTIA
The Annals of pharmacotherapy
PHARMACOKINETICS OF INTRACELLULAR ZIDOVUDINE AND ITS PHOSPHORYLATED ANABOLITES IN THE ABSENCE AND PRESENCE OF USING AN IN-VITRO HUMAN PERIPHERAL-BLOOD MONONUCLEAR CELL (PBMC) MODEL
International journal of antimicrobial agents
MICRODIALYSIS STUDIES OF THE DISTRIBUTION OF STAVUDINE INTO THE CENTRAL-NERVOUS-SYSTEM IN THE FREELY-MOVING RAT
Pharmaceutical research
ACETYL-CARNITINE DEFICIENCY IN AIDS PATIENTS WITH NEUROTOXICITY ON TREATMENT WITH ANTIRETROVIRAL NUCLEOSIDE ANALOGS
AIDS
CLINICAL EFFICACY OF MONOTHERAPY WITH STAVUDINE COMPARED WITH ZIDOVUDINE IN HIV-INFECTED, ZIDOVUDINE-EXPERIENCED PATIENTS - A RANDOMIZED, DOUBLE-BLIND, CONTROLLED TRIAL
Annals of internal medicine
EFFECT OF PREGNANCY, MODE OF ADMINISTRATION AND NEONATAL AGE ON THE PHARMACOKINETICS OF ZALCITABINE (2',3'-DIDEOXYCYTIDINE) IN THE PIGTAILED MACAQUE (MACACA-NEMESTRINA)
JAC. Journal of antimicrobial chemotherapy
3RD RETROVIRUS CONFERENCE - MAGIC
Complications in surgery
SPECIFIC RADIOIMMUNOASSAYS FOR THE MEASUREMENT OF STAVUDINE IN HUMAN PLASMA AND URINE
Journal of pharmaceutical and biomedical analysis
SYNTHESIS OF 1'-[C-14]-STAVUDINE(R) (D4T)
Journal of labelled compounds & radiopharmaceuticals
CLINICAL TOXICITY OF ANTIRETROVIRAL NUCLEOSIDE ANALOGS
Antiviral research