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Signalling pathways in Drosophila and vertebrate retinal development
NATURE REVIEWS GENETICS
Zebrafish genetics and vertebrate heart formation
NATURE REVIEWS GENETICS
Early eye development in vertebrates
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY
The upstream ectoderm enhancer in Pax6 has an important role in lens induction
DEVELOPMENT
Isolation and characterization of a downstream target of Pax6 in the mammalian retinal primordium
DEVELOPMENT
Otx genes are required for tissue specification in the developing eye
DEVELOPMENT
Roles of retinoic acid receptors in early embryonic morphogenesis and hindbrain patterning
DEVELOPMENT
Expression of evolutionarily conserved eye specification genes during Drosophila embryogenesis
DEVELOPMENT GENES AND EVOLUTION
Differential expression and function of the Drosophila Pax6 genes eyeless and twin of eyeless in embryonic central nervous system development
MECHANISMS OF DEVELOPMENT
The eyeless homeodomain is dispensable for eye development in Drosophila
GENES & DEVELOPMENT
Characterization of the murine Lbx2 promoter, identification of the human homologue, and evaluation as a candidate for Alstrom syndrome
GENOMICS
SHOX gene in Leri-Weill syndrome and in idiopathic short stature
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
Population-based risk estimates of Wilms tumor in sporadic aniridia - A comprehensive mutation screening procedure of PAX6 identifies 80% of mutations in aniridia
HUMAN GENETICS
Current concepts in tall stature and overgrowth syndromes
JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
Dach1 mutant mice bear no gross abnormalities in eye, limb, and brain development and exhibit postnatal lethality
MOLECULAR AND CELLULAR BIOLOGY
Pax genes in development and maturation of the vertebrate visual system: Implications for optic nerve regeneration
HISTOLOGY AND HISTOPATHOLOGY
Glial control of neuronal development
ANNUAL REVIEW OF NEUROSCIENCE
Genes regulating touch cell development in Caenorhabditis elegans
GENETICS
NF-kappa B mediates FGF signal regulation of msx-1 expression
DEVELOPMENTAL BIOLOGY
Temporal and spatial effects of Sonic hedgehog signaling in chick eye morphogenesis
DEVELOPMENTAL BIOLOGY
Function of Rx, but not Pax6, is essential for the formation of retinal progenitor cells in mice
GENESIS
Developmental patterning genes and their conserved functions: From model organisms to humans
MOLECULAR GENETICS AND METABOLISM
Mutation in the PAX6 gene in twenty patients with aniridia
HUMAN MUTATION
Vertebrate eye development as modeled in Drosophila
HUMAN MOLECULAR GENETICS
Increased levels of apoptosis in the prefusion neural folds underlie the craniofacial disorder, Treacher Collins syndrome
HUMAN MOLECULAR GENETICS
The conditional medaka mutation eyeless uncouples patterning and morphogenesis of the eye
DEVELOPMENT
Dosage requirement and allelic expression of PAX6 during lens placode formation
DEVELOPMENT
Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for Pax6 and Gsh2
DEVELOPMENT
Early development of the Drosophila mushroom body: the roles of eyeless and dachshund
DEVELOPMENT
Expanded retina territory by midbrain transformation upon overexpression of Six6 (Optx2) in Xenopus embryos
MECHANISMS OF DEVELOPMENT
Pax genes and the differentiation of hormone-producing endocrine cells in the pancreas
MECHANISMS OF DEVELOPMENT
HOXB7 overexpression promotes differentiation of C3H10T1/2 cells to smoothmuscle cells
JOURNAL OF CELLULAR BIOCHEMISTRY
A novel PAX6 gene mutation (P118R) in a family with congenital nystagmus associated with a variant form of aniridia
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
Roles for Msx and Dlx homeoproteins in vertebrate development
GENE
Congenital cataracts: gene mapping
HUMAN GENETICS
Expression and function of Xmsx-2B in dorso-ventral axis formation in gastrula embryos
ZOOLOGICAL SCIENCE
Pax6 modulates the dorsoventral patterning of the mammalian telencephalon
JOURNAL OF NEUROSCIENCE
3 ' deletions cause aniridia by preventing PAX6 gene expression
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Modulation of PAX6 homeodomain function by the paired domain
JOURNAL OF BIOLOGICAL CHEMISTRY
Pax-6 expression and activity are induced in the reepithelializing cornea and control activity of the transcriptional promoter for matrix metalloproteinase gelatinase B
DEVELOPMENTAL BIOLOGY
Altered retinoid signaling in the heads of small eye mouse embryos
DEVELOPMENTAL BIOLOGY
Analysis of gene expressions during Xenopus forelimb regeneration
DEVELOPMENTAL BIOLOGY
Monoallelic expression of Pax5: A paradigm for the haploinsufficiency of mammalian Pax genes?
BIOLOGICAL CHEMISTRY
Pax6 is implicated in murine pituitary endocrine function
ENDOCRINE
twin of eyeless, a second Pax-6 gene of Drosophila, acts upstream of eyeless in the control of eye development
MOLECULAR CELL
Vertebrate tinman homologues and cardiac differentiation
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
Mutational analysis of PAX6: 16 novel mutations including 5 missense mutations with a mild aniridia phenotype
EUROPEAN JOURNAL OF HUMAN GENETICS
Transcription factors for lens development assessed in vivo
CURRENT OPINION IN GENETICS & DEVELOPMENT
Involvement of poly(ADP-ribose)-polymerase in the Pax-6 gene regulation inneuroretina
ONCOGENE
Signaling by the TGF-beta homolog decapentaplegic functions reiteratively within the network of genes controlling retinal cell fate determination in Drosophila
DEVELOPMENT
Key roles of retinoic acid receptors alpha and beta in the patterning of the caudal hindbrain, pharyngeal arches and otocyst in the mouse
DEVELOPMENT
Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer
DEVELOPMENT
Mouse Dach, a homologue of Drosophila dachshund, is expressed in the developing retina, brain and limbs
DEVELOPMENT GENES AND EVOLUTION
High conservation of cis-regulatory elements between quail and human for the Pax-6 gene
DEVELOPMENT GENES AND EVOLUTION
Lens epithelial proliferation cataract in segmental trisomy involving mouse Chromosomes 4 and 17
MAMMALIAN GENOME
Identification and developmental expression of Ci-msxb: a novel homologue of Drosophila msh gene in Ciona intestinalis
MECHANISMS OF DEVELOPMENT
Six3 overexpression initiates the formation of ectopic retina
GENES & DEVELOPMENT
Tissue-specific transcriptional activity of a pancreatic islet cell-specific enhancer sequence/Pax6-binding site determined in normal adult tissues in vivo using transgenic mice
MOLECULAR ENDOCRINOLOGY
Quantitative estimation of RNA transcripts suggests persistence of Pax-6 expression in the postembryonic chick retina
DEVELOPMENTAL NEUROSCIENCE
The role of Xmsx-2 in the anterior-posterior patterning of the mesoderm inXenopus laevis
DIFFERENTIATION
Pax-6 and Prox 1 expression during lens regeneration from Cynops iris and Xenopus cornea: evidence for a genetic program common to embryonic lens development
DIFFERENTIATION
Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4
MOLECULAR AND CELLULAR BIOLOGY
A conserved blueprint for the eye?
BIOESSAYS
Expression pattern of PAX3 and PAX6 genes during human embryogenesis
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
Pax 6 - mastering eye morphogenesis and eye evolution
TRENDS IN GENETICS
Regulation of Prox 1 during lens regeneration
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Regulated expression of the bone-specific osteocalcin gene by vitamins andhormones
VITAMINS AND HORMONES - ADVANCES IN RESEARCH AND APPLICATIONS, VOL 55
Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Functional analysis of an eye specific enhancer of the eyeless gene in Drosophila
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Evidence that POU factor Brn-3b regulates expression of Pax-6 in neuroretina cells
JOURNAL OF NEUROBIOLOGY
Pax-6 and Cdx-2/3 interact to activate glucagon gene expression on the G(1) control element
JOURNAL OF BIOLOGICAL CHEMISTRY
Phosphorylation of the transactivation domain of Pax6 by extracellular signal-regulated kinase and p38 mitogen-activated protein kinase
JOURNAL OF BIOLOGICAL CHEMISTRY
Context-dependent transcriptional cooperation mediated by cardiac transcription factors Csx/Nkx-2.5 and GATA-4
JOURNAL OF BIOLOGICAL CHEMISTRY
Ectopic Msx2 overexpression inhibits and Msx2 antisense stimulates calvarial osteoblast differentiation
DEVELOPMENTAL BIOLOGY
Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods
DEVELOPMENTAL BIOLOGY
Distinct cis-essential modules direct the time-space pattern of the Pax6 gene activity
DEVELOPMENTAL BIOLOGY
Pax-6 expression during retinal regeneration in the adult newt
DEVELOPMENT GROWTH & DIFFERENTIATION
Glaucoma genetics, present and future
CLINICAL GENETICS
Pax genes and their role in organogenesis
CANCER RESEARCH
PAX6 expression in the developing human eye
BRITISH JOURNAL OF OPHTHALMOLOGY
Hox gene complexity in medaka fish may be similar to that in pufferfish rather than zebrafish
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
10 NOVEL MUTATIONS FOUND IN ANIRIDIA
Human mutation
PAX6 MUTATIONS REVIEWED
Human mutation
4 NOVEL AND 2 PREVIOUSLY REPORTED MUTATIONS OF THE PAX6 GENE IN PATIENTS WITH ANIRIDIA
Human mutation
POSITION EFFECT IN HUMAN GENETIC-DISEASE
Human molecular genetics (Print)
REGULATION IN THE HEART FIELD OF ZEBRAFISH
Development
GENE ACTIVATION DURING EARLY STAGES OF LENS INDUCTION IN XENOPUS
Development
ISOLATION AND DEVELOPMENTAL EXPRESSION OF THE AMPHIOXUS PAX-6 GENE (AMPHIPAX-6) - INSIGHTS INTO EYE AND PHOTORECEPTOR EVOLUTION
Development
Math5 encodes a murine basic helix-loop-helix transcription factor expressed during early stages of retinal neurogenesis
DEVELOPMENT
MOLECULAR REGULATORS INVOLVED IN VERTEBRATE EYE DEVELOPMENT
Mechanisms of development
SIGNALING INTERACTIONS DURING FACIAL DEVELOPMENT
Mechanisms of development
MAMMALIAN AND DROSOPHILA DACHSHUND GENES ARE RELATED TO THE SKI PROTOONCOGENE AND ARE EXPRESSED IN EYE AND LIMB
Mechanisms of development
CONTROL OF ANTEROPOSTERIOR AND DORSOVENTRAL DOMAINS OF NKX-6.1 GENE-EXPRESSION RELATIVE TO OTHER NKX GENES DURING VERTEBRATE CNS DEVELOPMENT
Mechanisms of development
THE DEVELOPMENT OF THE VERTEBRATE INNER-EAR
Mechanisms of development
Zebrafish contains two Pax6 genes involved in eye development
MECHANISMS OF DEVELOPMENT
Influence of anaesthetic agent on limb abnormalities observed following amniotic sac puncture
EUROPEAN JOURNAL OF MORPHOLOGY
PAX GENES AND ORGANOGENESIS - PAX9 MEETS TOOTH DEVELOPMENT
European journal of oral sciences
SOX1 DIRECTLY REGULATES THE GAMMA-CRYSTALLIN GENES AND IS ESSENTIAL FOR LENS DEVELOPMENT IN MICE
Genes & development
DIFFERENTIAL REGULATION OF BASAL AND CYCLIC ADENOSINE 3',5'-MONOPHOSPHATE-INDUCED SOMATOSTATIN GENE-TRANSCRIPTION IN NEURAL CELLS BY DNA CONTROL ELEMENTS THAT BIND HOMEODOMAIN PROTEINS
Molecular endocrinology
ISOLATION AND CHROMOSOMAL LOCALIZATION OF 2 HUMAN CDP-DIACYLGLYCEROL SYNTHASE (CDS) GENES
Genomics (San Diego, Calif.)