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Gene transfer into retinal ganglion cells by in vivo electroporation: a new approach
MICRON
The use of synthetic polymers for delivery of therapeutic antisense oligodeoxynucleotides
BIOMATERIALS
Adenovirus hexon protein is a potent adjuvant for activation of a cellularimmune response
JOURNAL OF VIROLOGY
Induction of immune tolerance toward tumor-associated-antigens enables growth of human hepatoma in mice
INTERNATIONAL JOURNAL OF CANCER
Comparison of different bioreactor systems for the production of high titer retroviral vectors
BIOTECHNOLOGY PROGRESS
Human bone marrow stromal cells are efficiently transduced by vesicular stomatitis virus-pseudotyped retrovectors without affecting subsequent osteoblastic differentiation
BONE
The effect of bone morphogenetic protein-2 expression on the early fate ofskeletal muscle-derived cells
BONE
A metaphyseal defect model of the femur for studies of murine bone healing
BONE
Myogenic satellite cells: physiology to molecular biology
JOURNAL OF APPLIED PHYSIOLOGY
Targeting head and neck cancer by IL-2-mediated gene therapy: From bench to bedside - A review.
LARYNGO-RHINO-OTOLOGIE
Transcriptional regulation in cancer gene therapy
ISRAEL MEDICAL ASSOCIATION JOURNAL
Intraarterial delivery of genetic vectors for the treatment of malignant brain tumors
ISRAEL MEDICAL ASSOCIATION JOURNAL
Materials for non-viral gene delivery
ANNUAL REVIEW OF MATERIALS RESEARCH
Methodologic issues in the conduct and interpretation of pediatric effectiveness research
AMBULATORY PEDIATRICS
Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation
NATURE IMMUNOLOGY
Novel therapies for pancreatic cancer
CANCER JOURNAL
Gene therapy: Promises and problems
ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS
Gene therapy for acute diseases
MOLECULAR THERAPY
Immune evasion by muscle-specific gene expression in dystrophic muscle
MOLECULAR THERAPY
Immediate and long-term safety of recombinant adeno-associated virus injection into the nonhuman primate muscle
MOLECULAR THERAPY
Lack of germline transmission of vector sequences following systemic administration of recombinant AAV-2 vector in males
MOLECULAR THERAPY
Regulated, adenovirus-mediated delivery of tyrosine hydroxylase suppressesgrowth of estrogen-induced pituitary prolactinomas
MOLECULAR THERAPY
Absence of germline infection in male mice following intraventricular injection of adenovirus
MOLECULAR THERAPY
Glial cell line derived neurotrophic factor delays photoreceptor degeneration in a transgenic rat model of retinitis pigmentosa
MOLECULAR THERAPY
A complex adenovirus vector that delivers FASL-GFP with combined prostate-specific and tetracycline-regulated expression
MOLECULAR THERAPY
Retroviral vectors for the transduction of autoregulated, bidirectional expression cassettes
MOLECULAR THERAPY
Forced myofiber regeneration promotes dystrophin gene transfer and improved muscle function despite advanced disease in old dystrophic mice
MOLECULAR THERAPY
Noninvasive optical imaging of firefly luciferase reporter gene expressionin skeletal muscles of living mice
MOLECULAR THERAPY
Combined administration of plasmids encoding IL-4 and IL-10 prevents the development of autoimmune diabetes in nonobese diabetic mice
MOLECULAR THERAPY
Slow accumulation of plasmid in muscle cells: Supporting evidence for a mechanism of DNA uptake by receptor-mediated endocytosis
MOLECULAR THERAPY
Functional effect of adeno-associated virus mediated gene transfer of aromatic L-amino acid decarboxylase into the striatum of 6-OHDA-lesioned rats
MOLECULAR THERAPY
Gene therapy of a mouse model of protoporphyria with a self-inactivating erythroid-specific lentiviral vector without preselection
MOLECULAR THERAPY
High-level, beta-catenin/TCF-dependent transgene expression in secondary colorectal cancer tissue
MOLECULAR THERAPY
Multigene lentiviral vectors based on differential splicing and translational control
MOLECULAR THERAPY
Expanding AAV packaging capacity with trans-splicing or overlapping vectors: A quantitative comparison
MOLECULAR THERAPY
Modified HIV-1 based lentiviral vectors have an effect on viral transduction efficiency and gene expression in vitro and in vivo
MOLECULAR THERAPY
Efficient and selective AAV2-mediated gene transfer directed to human vascular endothelial cells
MOLECULAR THERAPY
Intratumoral adenovirus-mediated suicide gene transfer for hepatic metastases from colorectal adenocarcinoma: Results of a phase I clinical trial
MOLECULAR THERAPY
An adenovirus with enhanced infectivity mediates molecular chemotherapy ofovarian cancer cells and allows imaging of gene expression
MOLECULAR THERAPY
VSV-G envelope glycoprotein forms complexes with plasmid DNA and MLV retrovirus-like particles in cell-free conditions and enhances DNA transfection
MOLECULAR THERAPY
Imaging transgene expression in live animals
MOLECULAR THERAPY
Suppression of tumor growth following intralesional therapy with TRAIL recombinant adenovirus
MOLECULAR THERAPY
Glucocorticoid-regulated expression of exogenous human growth hormone genein rats
MOLECULAR THERAPY
A packaging cell line generating CD4-specific retroviral vectors for efficient gene transfer into primary human T-helper lymphocytes
MOLECULAR THERAPY
Development of an MFG-based retroviral vector system for secretion of highlevels of functionally active human BMP4
MOLECULAR THERAPY
Messenger RNA repair and restoration of protein function by spliceosome-mediated RNA trans-splicing
MOLECULAR THERAPY
In utero AAV-mediated gene transfer to rabbit pulmonary epithelium
MOLECULAR THERAPY
Epstein-Barr virus/human vector provides high-level, long-term expression of alpha(1)-antitrypsin in mice
MOLECULAR THERAPY
Dose-dependent effects of central leptin gene therapy on genes that regulate body weight and appetite in the hypothalamus
MOLECULAR THERAPY
Elimination of the truncated message from the herpes simplex virus thymidine kinase suicide gene
MOLECULAR THERAPY
Enhanced apoptotic activity of a p53 variant in tumors resistant to wild-type p53 treatment
MOLECULAR THERAPY
Development of novel formulations that enhance adenoviral-mediated gene expression in the lung in vitro and in vivo
MOLECULAR THERAPY
Intra-arterial delivery of a recombinant adenovirus does not increase genetransfer to tumor cells in a rat model of metastatic colorectal carcinoma
MOLECULAR THERAPY
Targeting transgene expression for cystic fibrosis gene therapy
MOLECULAR THERAPY
Regulation of angiogenesis and matrix remodeling by localized, matrix-mediated antisense gene delivery
MOLECULAR THERAPY
In vivo treatment of hemophilia A and mucopolysaccharidosis type VII usingnonprimate lentiviral vectors
MOLECULAR THERAPY
Tail-vein injection of mannan-binding lectin DNA leads to high expression levels of multimeric protein in liver
MOLECULAR THERAPY
Primary adult human astrocytes as an ex vivo vehicle for beta-glucuronidase delivery in the brain
MOLECULAR THERAPY
Targeting of adenovirus to endothelial cells by a bispecific single-chain diabody directed against the adenovirus fiber knob domain and human endoglin (CD105)
MOLECULAR THERAPY
Gene transfer of p53 to arthritic joints stimulates synovial apoptosis andinhibits inflammation
MOLECULAR THERAPY
Adeno-associated virus 2-mediated transduction and erythroid lineage-restricted long-term expression of the human beta-globin gene in hematopoietic cells from homozygous beta-thalassemic mice
MOLECULAR THERAPY
HSV amplicon-mediated neurotrophin-3 expression protects murine spiral ganglion neurons from cisplatin-induced damage
MOLECULAR THERAPY
Incorporation of tumor-targeting peptides into recombinant adeno-associated virus capsids
MOLECULAR THERAPY
A regulated, NF kappa B-assisted import of plasmid DNA into mammalian cellnuclei
MOLECULAR THERAPY
alpha(v)beta(3) integrin-mediated adenoviral transfer of interleukin-12 atthe periphery of hepatic colon cancer metastases induces VCAM-1 expressionand T-cell recruitment
MOLECULAR THERAPY
Hyper-IL-6 gene therapy reverses fulminant hepatic failure
MOLECULAR THERAPY
Recombinant AAV-mediated delivery of a tet-inducible reporter gene to the rat retina
MOLECULAR THERAPY
Acute cytokine response to systemic adenoviral vectors in mice is mediatedby dendritic cells and macrophages
MOLECULAR THERAPY
Use of perfluorochemical liquid allows earlier detection of gene expression and use of less vector in normal lung and enhances gene expression in acutely injured lung
MOLECULAR THERAPY
TNF alpha and IFN gamma induced by innate anti-adenoviral immune responsesinhibit adenovirus-mediated transgene expression
MOLECULAR THERAPY
Coexpression of guanylate kinase with thymidine kinase enhances prodrug cell killing in vitro and suppresses vascular smooth muscle cell proliferation in vivo
MOLECULAR THERAPY
Quantitative PCR-ELAHA for the determination of retroviral vector transduction efficiency
MOLECULAR THERAPY
Development of a FLP/frt system for generating helper-dependent adenoviralvectors
MOLECULAR THERAPY
A death in the laboratory: The politics of the Gelsinger aftermath
MOLECULAR THERAPY
Therapeutic efficacy of G207, a conditionally replicating herpes simplex virus type 1 mutant, for gallbladder carcinoma in immunocompetent hamsters
MOLECULAR THERAPY
Exogenously regulated stem cell-mediated gene therapy for bone regeneration
MOLECULAR THERAPY
Lipopolysaccharide potentiates the effect of hepatocyte growth factor uponreplication in lung, thyroid, spleen, and colon in rats in vivo
MOLECULAR THERAPY
Receptor-targeted gene delivery using multivalent phagemid particles
MOLECULAR THERAPY
In vivo surgical resection plus adjuvant gene therapy in the treatment of mammary and prostate cancer
MOLECULAR THERAPY
Two animal models of retinal degeneration are rescued by recombinant adeno-associated virus-mediated production of FGF-5 and FGF-18
MOLECULAR THERAPY
Smaller amounts of antiretroviral drugs are needed when combined with an active ribozyme against HIV-1
MOLECULAR THERAPY
Enhanced therapeutic effect of HSV-tk plus GCV gene therapy and ionizing radiation for prostate cancer
MOLECULAR THERAPY
Bone-directed expression of Col1a1 promoter-driven self-inactivating retroviral vector in bone marrow cells and transgenic mice
MOLECULAR THERAPY
Transgene expression in mouse airway epithelium by aerosol gene therapy with PEI-DNA complexes
MOLECULAR THERAPY
Comparison of five retrovirus vectors containing the human IL-2 receptor gamma chain gene for their ability to restore T and B lymphocytes in the X-linked severe combined immunodeficiency mouse model
MOLECULAR THERAPY
Auto-regulated hepatic insulin gene expression in type 1 diabetic rats
MOLECULAR THERAPY
Improved helper virus-free packaging system for HSV amplicon vectors usingan ICP27-deleted, oversized HSV-1 DNA in a bacterial artificial chromosome
MOLECULAR THERAPY
Streptavidin paramagnetic particles provide a choice of three affinity-based capture and magnetic concentration strategies for retroviral vectors
MOLECULAR THERAPY
Characterization of cis-acting sequences involved in canine adenovirus packaging
MOLECULAR THERAPY
Augmenting transgene expression from carcinoembryonic antigen (CEA) promoter via a GAL4 gene regulatory system
MOLECULAR THERAPY
In utero delivery of adeno-associated viral vectors: Intraperitoneal gene transfer produces long-term expression
MOLECULAR THERAPY
An immunomodulatory procedure that stabilizes transgene expression and permits readministration of E1-deleted adenovirus vectors
MOLECULAR THERAPY
Two point mutations increase targeted transduction and stabilize vector association of a modified retroviral envelope protein
MOLECULAR THERAPY
Successful treatment of primary and disseminated human lung cancers by systemic delivery of tumor suppressor genes using an improved liposome vector
MOLECULAR THERAPY
Intracranial injection of recombinant adeno-associated virus improves cognitive function in a murine model of mucopolysaccharidosis type VII
MOLECULAR THERAPY
Fibronectin fragment CH-296 inhibits apoptosis and enhances ex vivo gene transfer by murine retrovirus and human lentivirus vectors independent of viral tropism in nonhuman primate CD34(+) cells
MOLECULAR THERAPY
Regression of human mammary adenocarcinoma by systemic administration of arecombinant gene encoding the hFlex-TRAIL fusion protein
MOLECULAR THERAPY
Infection of human airway epithelia with H1N1, H2N2, and H3N2 influenza A virus strains
MOLECULAR THERAPY
Linear DNAs concatemerize in vivo and result in sustained transgene expression in mouse liver
MOLECULAR THERAPY
Correction of deficient CD34(+) cells from peripheral blood after mobilization in a patient with congenital erythropoietic porphyria
MOLECULAR THERAPY