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Titolo:
Molecular evolution of the GDP-mannose pathway genes (manB and manC) in Salmonella enterica
Autore:
Jensen, SO; Reeves, PR;
Indirizzi:
Univ Sydney, Dept Microbiol, Sydney, NSW 2006, Australia Univ Sydney Sydney NSW Australia 2006 robiol, Sydney, NSW 2006, Australia
Titolo Testata:
MICROBIOLOGY-UK
, volume: 147, anno: 2001,
parte:, 3
pagine: 599 - 610
SICI:
1350-0872(200103)147:<599:MEOTGP>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
DIRECTIONAL MUTATION PRESSURE; ESCHERICHIA-COLI K-12; O-ANTIGEN; DNA-SEQUENCE; NATURAL-POPULATIONS; GROUP-B; CLUSTER; RFB; STRAIN; POLYMORPHISM;
Keywords:
concerted evolution; GDP-D-mannose pathway; gene conversion; lateral transfer; Salmonella enterica;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
47
Recensione:
Indirizzi per estratti:
Indirizzo: Reeves, PR Univ Sydney, Dept Microbiol, Sydney, NSW 2006, Australia Univ Sydney Sydney NSW Australia 2006 ney, NSW 2006, Australia
Citazione:
S.O. Jensen e P.R. Reeves, "Molecular evolution of the GDP-mannose pathway genes (manB and manC) in Salmonella enterica", MICROBIO-UK, 147, 2001, pp. 599-610

Abstract

The evolutionary history of the CDP-mannose pathway in Salmonella entericawas studied via sequencing manB and manC genes from 13 representative strains for O antigens containing mannose and/or sugar derivatives of CDP-D-mannose. In addition, colanic acid (CA) manB and manC genes were sequenced from selected strains, as the basis for a detailed comparison. interestingly, including the eight previously characterized O antigen gene clusters, 12 ofthe 21 S. enterica strains studied in total teach representing a differentO antigen structure) possess a manB gene which displays DNA identity, ranging from 93 to 99%, to the CA manB gene of S. enterica LT2. Furthermore, the CA-like manB genes las well as the CA manB and manC genes) display subspecies specificity, and the CA and CA-like manB genes (for individual strains) appear to be evolving in concert via gene conversion events. In comparison, the manC genes were generally not CA-like, a situation also apparent in Escherichia coli, and therefore most strongly reflected the evolutionary history of the S. enterica O antigen GDP-mannose pathway. It appears that, inrelatively recent times, gene capture from a distant source has occurred infrequently, and that groups of manB and manC genes have keen maintained and are continuing to evolve within S, enterica and more closely related species.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/12/17 alle ore 23:39:26