Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
An efficient synthetic route to chiral 4-alkyl-1,2,3,4-tetrahydroquinolines: enantioselective synthesis of (R)-4-ethyl-1,2,3,4-tetrahydroquinoline
Autore:
Mani, NS; Wu, M;
Indirizzi:
Ligand Pharmaceut Inc, Dept Med Chem, San Diego, CA 92121 USA Ligand Pharmaceut Inc San Diego CA USA 92121 hem, San Diego, CA 92121 USA
Titolo Testata:
TETRAHEDRON-ASYMMETRY
fascicolo: 23, volume: 11, anno: 2000,
pagine: 4687 - 4691
SICI:
0957-4166(200012)11:23<4687:AESRTC>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
BECKMANN REARRANGEMENT; REAGENTS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Mani, NS RW Johnson Pharmaceut Res Inst, 3210 Merryfield Row, San Diego, CA 92121 USA RW Johnson Pharmaceut Res Inst 3210 Merryfield Row San Diego CAUSA 92121
Citazione:
N.S. Mani e M. Wu, "An efficient synthetic route to chiral 4-alkyl-1,2,3,4-tetrahydroquinolines: enantioselective synthesis of (R)-4-ethyl-1,2,3,4-tetrahydroquinoline", TETRAHEDR-A, 11(23), 2000, pp. 4687-4691

Abstract

An efficient synthetic route to non-racemic chiral 4-alkyl-1,2,3,4-tetrahydpoquinoline is described. (4R)-4-Ethyl- 1,2,3,4-tetrahydroquinoline was obtained by the organoaluminum promoted modified Beckmann rearrangement involving the oxime sulfonate of (3R)-3-ethylindan-1 -one. The required optically active indanone was obtained via an asymmetric conjugate reduction of (E)-ethyl 3-phenylpent-2-enoate. (C) 2001 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/11/17 alle ore 05:50:58